Department of Biomedical Sciences

University of Missouri

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Recent Publications

Gamma-Aminobutyric Acid Transporters in the Nucleus Tractus Solitarii Regulate Inhibitory and Excitatory Synaptic Currents That Influence Cardiorespiratory Function.
Martinez D, Lima-Silveira L, Matott MP, Hasser EM, Kline DD.
Front Physiol. 2022 Jan 14;12:821110. doi: 10.3389/fphys.2021.821110. eCollection 2021. PMID: 35095576

The estrogen receptor beta agonist liquiritigenin enhances the inhibitory effects of the cholesterol biosynthesis inhibitor RO 48-8071 on hormone-dependent breast-cancer growth.
Liang Y, Besch-Williford C, Hyder SM.
Breast Cancer Res Treat. 2022 Jan 17. doi: 10.1007/s10549-021-06487-y. PMID: 35037188

Role of Reactivating Mutant p53 Protein in Suppressing Growth and Metastasis of Triple-Negative Breast Cancer.
Berke TP, Slight SH, Hyder SM.
Onco Targets Ther. 2022 Jan 8;15:23-30. doi: 10.2147/OTT.S342292. eCollection 2022. PMID: 35035222

The placenta as a target of opioid drugs.
Rosenfeld CS.
Biol Reprod. 2022 Jan 12:ioac003. doi: 10.1093/biolre/ioac003. PMID: 35024817

The impact of bisphenol a (BPA) on the placenta.
Adu-Gyamfi EA, Rosenfeld CS, Tuteja G.
Biol Reprod. 2022 Jan 8:ioac001. doi: 10.1093/biolre/ioac001. PMID: 35020819

Hepatocyte-specific eNOS deletion impairs exercise-induced adaptations in hepatic mitochondrial function and autophagy.
Cunningham RP, Moore MP, Dashek RJ, Meers GM, Jepkemoi V, Takahashi T, Vieira-Potter VJ, Kanaley JA, Booth FW, Rector RS.
Obesity (Silver Spring). 2022 Mar 31. doi: 10.1002/oby.23414. PMID: 35357089

A ‘Swine Time’ for HFpEF: Multiple animal models for a myriad of clinical phenotypes.
Emter CA.
J Mol Cell Cardiol. 2022 Mar 19;167:15-16. doi: 10.1016/j.yjmcc.2022.03.004. PMID: 35318042

Mechanism-Driven Modeling to Aid Non-invasive Monitoring of Cardiac Function via Ballistocardiography.
Zaid M, Sala L, Ivey JR, Tharp DL, Mueller CM, Thorne PK, Kelly SC, Silva KAS, Amin AR, Ruiz-Lozano P, Kapiloff MS, Despins L, Popescu M, Keller J, Skubic M, Ahmad S, Emter CA, Guidoboni G.
Front Med Technol. 2022 Feb 16;4:788264. doi: 10.3389/fmedt.2022.788264. eCollection 2022. PMID: 35252962

Impact of Limb Phenotype on Tongue Denervation Atrophy, Dysphagia Penetrance, and Survival Time in a Mouse Model of ALS.
Mueller M, Thompson R, Osman KL, Andel E, DeJonge CA, Kington S, Stephenson Z, Hamad A, Bunyak F, Nichols NL, Lever TE.
Dysphagia. 2022 Apr 15. doi: 10.1007/s00455-022-10442-4. PMID: 35426522

Orexin facilitates the ventilatory and behavioral responses of rats to hypoxia.
Spinieli RL, Ben Musa R, Cornelius-Green J, Hasser EM, Cummings KJ.
Am J Physiol Regul Integr Comp Physiol. 2022 Apr 5. doi: 10.1152/ajpregu.00334.2021. PMID: 35380477

Distribution of cardiomyocyte-selective adeno-associated virus serotype 9 vectors in swine following intracoronary and intravenous infusion.
Li J, Kelly SC, Ivey JR, Thorne PK, Yamada KP, Aikawa T, Mazurek R, Turk JR, Silva KAS, Amin AR, Tharp DL, Mueller CM, Thakur H, Leary EV, Domeier TL, Rector RS, Fish K, Cividini F, Ishikawa K, Emter CA, Kapiloff MS.
Physiol Genomics. 2022 Jun 1. doi: 10.1152/physiolgenomics.00032.2022. PM ID: 35648460

Cardiovascular deconditioning increases GABA signaling in the nucleus tractus solitarii.
Lima-Silveira L, Hasser EM, Kline DD.
J Neurophysiol. 2022 Jun 1. doi: 10.1152/jn.00102.2022. PMID: 35642806  

Assessing central and peripheral respiratory chemoreceptor interaction in humans.
Milloy KM, White MG, Chicilo JOC, Cummings KJ, Pfoh JR, Day TA.
Exp Physiol. 2022 Jun 29. doi: 10.1113/EP089983. PMID: 357661272

Temporal Changes in Coronary Artery Function and Flow Velocity Reserve in Mice Exposed to Chronic Intermittent Hypoxia.
Badran M, Bender SB, Khalyfa A, Padilla J, Martinez-Lemus LA, Gozal D.
Sleep. 2022 Jun 6:zsac131. doi: 10.1093/sleep/zsac131. PMID: 35661901

Long-Term Effects of Developmental Exposure to Oxycodone on Gut Microbiota and Relationship to Adult Behaviors and Metabolism.
Lyu Z, Schmidt RR, Martin RE, Green MT, Kinkade JA, Mao J, Bivens NJ, Joshi T, Rosenfeld CS.
mSystems. 2022 Jul 7:e0033622. doi: 10.1128/msystems.00336-22. PMID: 35862801

A Strength Endurance Exercise Paradigm Mitigates Deficits in Hypoglossal-Tongue Axis Function, Strength, and Structure in a Rodent Model of Hypoglossal Motor Neuron Degeneration.
Murphy ER, Thompson R, Osman KL, Haxton C, Brothers M, Lee L, Warncke K, Smith CL, Keilholz AN, Hamad A, Golzy M, Bunyak F, Ma L, Nichols NL, Lever TE.
Front Neurosci. 2022 Jun 30;16:869592. doi: 10.3389/fnins.2022.869592. eCollection 2022. PMID: 35844238

Gut microbiota mediate vascular dysfunction in a murine model of sleep apnea: effect of probiotics.
Badran M, Khalyfa A, Ericsson A, Puech C, McAdams Z, Bender SB, Gozal D.
Eur Respir J. 2022 Aug 25:2200002. doi: 10.1183/13993003.00002-2022.
PMID: 36028255

A serotonin-deficient rat model of neurogenic hypertension: influence of sex and sympathetic vascular tone.
Spinieli RL, Cornelius-Green J, Cummings KJ.
J Neurophysiol. 2022 Sep 28. doi: 10.1152/jn.00358.2022. PMID: 36169206

Suppression of estrogen receptor beta classical genomic activity enhances systemic and adipose-specific response to chronic beta-3 adrenergic receptor (β3AR) stimulation.
Queathem ED, Fitzgerald M, Welly R, Rowles CC, Schaller K, Bukhary S, Baines CP, Rector RS, Padilla J, Manrique-Acevedo C, Lubahn DB, Vieira-Potter VJ
Front Physiol. 2022 Sep 16;13:920675. doi: 10.3389/fphys.2022.920675. eCollection 2022. PMID: 36213237

Contributions of physical inactivity and sedentary behavior to metabolic and endocrine diseases.
Kerr NR, Booth FW
Trends Endocrinol Metab. 2022 Oct 22:S1043-2760(22)00177-1. doi: 10.1016/j.tem.2022.09.002. PMID: 36283907 Review

Chronic high-rate pacing induces heart failure with preserved ejection fraction-like phenotype in Ossabaw swine.
Tune JD, Goodwill AG, Baker HE, Dick GM, Warne CM, Tucker SM, Essajee SI, Bailey CA, Klasing JA, Russell JJ, McCallinhart PE, Trask AJ, Bender SB
Basic Res Cardiol. 2022 Oct 12;117(1):50. doi: 10.1007/s00395-022-00958-z. PMID: 36222894

Preclinical evaluation of new C-11 labeled benzo-1,4-dioxane PET radiotracers for brain α2C adrenergic receptors.
Alluri S, Eisenberg SM, Grisanti LA, Tanner M, Volkow ND, Kim SW, Kil KE
Eur J Med Chem. 2022 Dec 5;243:114764. doi: 10.1016/j.ejmech.2022.114764. Epub 2022 Sep 17. PMID: 36272201

Graduate Studies in Biomedical Sciences

At the Department of Biomedical Sciences, investigators are engaged in research across a variety of fields, including cancer, neurodegenerative disease, exercise, cardiovascular, gastrointestinal, respiratory and reproductive physiology.

With world-class and award-winning researchers, our graduate program has a great deal to offer.

Find out more.

Faculty Spotlight

Lane L. Clarke, DVM, PhD

News

  • Expertise, Collegiality Earn Tommy Thompson Dean’s Impact Award
  • SEC Emerging Scholars Program Helps Guide Career Options for Biomedical Sciences Fellow
  • Prenatal Opioid Exposure May Trigger Neurological, Behavioral Changes Later in Life
  • Research With Heart
  • Retired Associate Dean Ronald L. Terjung Passes Away

Contact

Department of Biomedical Sciences
University of Missouri-Columbia
E102 Veterinary Medical Building
1520 Rollins Street
Columbia, MO 65211
Phone: 573-882-7011
Fax: 573-884-6890

 

Administrative Contacts

Dr. Douglas Bowles
Department Chair

BowlesD@missouri.edu
573-882-7193

Dr. Kevin Cummings
Director of Graduate Studies
cummingske@missouri.edu
573-882-0283

Thomas Thompson
Business Manager

ThompsonT@missouri.edu
573-882-4503

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